Description

4-Amino-3-Chloro-5-Trifluoromethyl-Benzoic Acid is a high-purity, multi-functional aromatic building block of significant commercial importance. Its unique trifluoromethyl-substituted benzoic acid structure makes it a critical intermediate for synthesizing advanced molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its aromaticity and functional handles.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments, where the amino and carboxylic acid groups allow for further chemical modifications.
• Polymer & Resin Modifier: Acts as a monomer or cross-linking agent to introduce specific functional groups into polymer chains, enhancing material properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic routes and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	4-Amino-3-Chloro-5-Trifluoromethyl-Benzoic Acid
CAS No.	95656-52-3
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	3-Chloro-4-amino-5-(trifluoromethyl)benzoic acid; 5-Trifluoromethyl-3-chloro-4-aminobenzoic acid; Benzoic acid, 4-amino-3-chloro-5-(trifluoromethyl)-; 4-Amino-3-chloro-α,α,α-trifluoro-m-toluic acid; 3-Chloro-4-amino-α,α,α-trifluoro-m-toluic acid; 4-Amino-3-chloro-5-trifluoromethylbenzoic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-5-Trifluoromethyl-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.