Description

1-(n-Acetylmuramyl-Alanyl-Isoglutaminyl)-2,3-Dipalmitoyl-Sn-Glycerol is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its potent immunomodulatory and adjuvant activities, making it a valuable tool in immunological research and vaccine development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on novel immunotherapies and vaccine formulations.

Application

• Immunological Research: As a potent synthetic adjuvant to study innate immune responses, particularly through NOD2 receptor activation.
• Vaccine Development: Used in the formulation of experimental vaccines to enhance immunogenicity and efficacy.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex immunostimulatory compounds.
• Cell Culture & In Vitro Studies: Applied in assays to investigate macrophage activation, cytokine production, and signaling pathways.
• Drug Delivery Systems: Incorporated into liposomal or nanoparticle-based delivery platforms for targeted immune stimulation.
• Comparative Adjuvant Studies: Used as a reference standard to evaluate the activity of new immunomodulatory agents.

Basic Information

Product Name	1-(n-Acetylmuramyl-Alanyl-Isoglutaminyl)-2,3-Dipalmitoyl-Sn-Glycerol
CAS No.	95238-29-2
Molecular Formula	C73H127N7O19
Molecular Weight	1438.83 g/mol
Synonyms	MDP-Glycerol Dipalmitate; Muramyl Dipeptide Glycerol Dipalmitate; L-Alanyl-D-isoglutaminyl-N-acetylmuramyl-2,3-dipalmitoyl-sn-glycerol; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-2,3-dipalmitoyl-sn-glycerol; Ac-MDP-Glycerol-Dipalmitate; MDP-GDP; Immunoadjuvant Peptidoglycan Fragment; 1-(N-Acetylmuramoyl-L-alanyl-D-isoglutaminyl)-2,3-di-O-palmitoyl-sn-glycerol
EINECS	Contact for details

Quality Control

Our high-purity biochemicals are manufactured under strict quality management systems. Each batch of 1-(n-Acetylmuramyl-Alanyl-Isoglutaminyl)-2,3-Dipalmitoyl-Sn-Glycerol undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in chloroform, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.