Description

(+-)-Tamsulosin CAS NO 94666-07-6 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) used in the synthesis of therapeutic agents. This compound is of critical importance for its role as a key building block in the production of α-1 adrenergic receptor antagonists, which are vital for treating conditions like benign prostatic hyperplasia (BPH). It is primarily required by pharmaceutical manufacturers, research and development (R&D) laboratories, and contract development and manufacturing organizations (CDMOs) engaged in the development and production of urological medications.

Application

• Pharmaceutical API Synthesis: Primary use as an intermediate in the commercial-scale manufacturing of Tamsulosin hydrochloride, the active ingredient in medications for benign prostatic hyperplasia (BPH).
• Research & Development: Serves as a critical reference standard and starting material in medicinal chemistry programs for developing new α-blockers or optimizing existing synthetic pathways.
• Generic Drug Production: Essential for manufacturers producing generic versions of BPH treatments, ensuring a reliable supply of a key chiral intermediate.
• Process Development & Scale-Up: Used in pilot plants and process chemistry to develop efficient, cost-effective, and scalable synthesis routes for pharmaceutical production.
• Analytical Standard: Employed in quality control (QC) and analytical laboratories as a high-purity standard for method development, validation, and impurity profiling via HPLC, GC, or spectroscopy.

Basic Information

Product Name	(+-)-Tamsulosin
CAS No.	94666-07-6
Molecular Formula	C20H28N2O5S
Molecular Weight	408.51 g/mol
Synonyms	(±)-Tamsulosin; Tamsulosin Racemate; (R,S)-Tamsulosin; 5-[(2R,3S)-2-Ethoxy-5-[(2-{[2-(2,2,2-trifluoroethoxy)phenyl]sulfonyl}amino)ethyl]phenoxy]propane-1,2-diol; YM-12617 (free base); DL-Tamsulosin; ABBOTT-64077; (±)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide
EINECS	Contact for details

Quality Control

Our (+-)-Tamsulosin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, with testing performed using validated methods such as HPLC, GC, and NMR. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.