Description

Tolterodine Tartrate is the tartrate salt form of tolterodine, a competitive muscarinic receptor antagonist. This active pharmaceutical ingredient (API) is critical for the formulation of medications designed to manage overactive bladder (OAB) syndrome, providing relief from symptoms such as urinary urgency, frequency, and incontinence. It is an essential raw material for pharmaceutical manufacturers developing and producing antimuscarinic drugs. The compound is supplied under the identifier CAS NO 124937-52-6.

Application

The primary and exclusive application of Tolterodine Tartrate is within the pharmaceutical industry. Its specific uses include:

• Active Pharmaceutical Ingredient (API): The core component in the manufacture of finished dosage forms for the treatment of overactive bladder.
• Immediate-Release Tablet Formulations: Used in tablets designed for rapid onset of therapeutic effect.
• Extended-Release Capsule Formulations: A key ingredient in controlled-release dosage forms that provide sustained drug delivery over time.
• Generic Drug Production: Serves as the fundamental API for manufacturers producing bioequivalent versions of branded antimuscarinic medications.
• Clinical Trial Material: Supplied as a high-purity compound for use in pharmaceutical research and development stages.

Basic Information

Product Name	Tolterodine Tartrate
CAS No.	124937-52-6
Molecular Formula	C26H37NO7
Molecular Weight	475.58 g/mol
Synonyms	(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-methylphenol L-Hydroxybutanedioate (1:1); Tolterodine L-Tartrate; Detrol; PNU-200583E; (R)-N,N-Diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine L-Tartrate; 2-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-methylphenyl (2R,3R)-2,3-dihydroxybutanedioate
EINECS	Contact for details

Quality Control

Our Tolterodine Tartrate is manufactured and tested to meet stringent pharmaceutical-grade standards. Quality assurance protocols are designed to ensure identity, purity, strength, and composition. We can supply material compliant with major pharmacopeial monographs, including USP and EP. A comprehensive Certificate of Analysis (COA) documenting all release tests is provided with each batch to ensure full traceability and regulatory compliance for our customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Optical Rotation	Specific range provided on COA
Microbial Limits	Meets Ph. Eur. 2.6.12 / USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.