Description

Trospium Dehydro Chloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is of significant commercial importance for its critical role in the synthesis of anticholinergic medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of urological and gastrointestinal therapeutics.

Application

• Primary Active Pharmaceutical Ingredient (API) for the manufacture of Trospium Chloride, a quaternary ammonium anticholinergic.
• Key Intermediate in the synthesis of medications for overactive bladder (OAB) syndrome and urinary incontinence.
• Research Chemical for pharmacological studies targeting muscarinic acetylcholine receptors.
• Reference Standard in analytical laboratories for quality control and method development using HPLC and LC-MS.
• Process Development material for optimizing scalable synthesis routes in fine chemical production.
• Formulation Development for creating stable and bioavailable dosage forms such as tablets and capsules.

Basic Information

Product Name	Trospium Dehydro Chloride
CAS No.	113922-55-7
Molecular Formula	C25H30ClNO3
Molecular Weight	427.97 g/mol
Synonyms	(1R,3R,5S)-3-[(Hydroxydiphenylacetyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane Chloride; Trospium Dehydrochloride; Trospium Chloride Impurity; Trospium Related Compound A; Spasmolyt; Spasmo Urgenin; 8-Azabicyclo[3.2.1]octane-3-ol, 8-methyl-, 3-hydroxy-2,2-diphenylpropanoate (ester), hydrochloride, (1R,3R,5S)-
EINECS	Contact for details

Quality Control

Our Trospium Dehydro Chloride is manufactured under strict quality management systems. We provide material that meets stringent specifications for pharmaceutical intermediates, with testing typically including identification, assay, and control of related substances and residual solvents. A comprehensive Certificate of Analysis (COA) is supplied with each batch, detailing compliance with agreed specifications. Our quality commitment aligns with cGMP principles for API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.