Description

Acetohydroxamic Acid is a potent and specific urease inhibitor, playing a critical role in controlling ammonia production in various chemical and biological systems. Its primary value lies in its ability to effectively block the enzymatic activity of urease, which is essential for applications ranging from medical research to industrial processes. This compound is particularly needed by manufacturers in the pharmaceutical, agricultural chemical, and research & development sectors seeking reliable, high-purity active ingredients.

Application

• Pharmaceutical Intermediate: Key starting material or active moiety in the synthesis of therapeutic agents, particularly those targeting urea-splitting bacteria.
• Urease Inhibition Research: Essential biochemical tool for in vitro and in vivo studies investigating urease-related pathways, enzyme kinetics, and metabolic disorders.
• Agricultural Chemistry: Used in the development of soil treatments and fertilizers designed to control urea hydrolysis rates, improving nitrogen use efficiency.
• Diagnostic Reagents: Component in clinical diagnostic kits and assays for the detection and quantification of urea or urease activity.
• Microbiological Control: Applied in studies targeting urease-positive pathogens, such as *Helicobacter pylori* and certain urinary tract infection-causing bacteria.
• Industrial Enzyme Inhibition: Employed in processes where uncontrolled urease activity is detrimental, such as in specific fermentation or waste treatment operations.

Basic Information

Product Name	Acetohydroxamic Acid
CAS No.	546-88-3
Molecular Formula	C2H5NO2
Molecular Weight	75.07 g/mol
Synonyms	N-Hydroxyacetamide; Acetylhydroxamic Acid; AHA; N-Acetylhydroxylamine; Hydroxyurea, N-acetyl-; Lithostat; NSC 48796; Urease Inhibitor AHA
EINECS	208-913-8

Quality Control

Our Acetohydroxamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	89°C - 92°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.