Description

Dutasteride CAS NO 164656-23-9 is a potent and selective dual inhibitor of both type I and type II 5α-reductase enzymes, which are responsible for the conversion of testosterone to dihydrotestosterone (DHT). This mechanism of action makes it a critical active pharmaceutical ingredient (API) for the treatment of androgen-dependent conditions. It is primarily required by pharmaceutical manufacturers and research institutions developing therapies for benign prostatic hyperplasia (BPH) and androgenic alopecia. Our high-purity Dutasteride ensures reliable performance and consistency in final drug formulations.

Application

• Primary Active Pharmaceutical Ingredient (API) in prescription medications for the treatment of Benign Prostatic Hyperplasia (BPH).
• Key component in formulations for male pattern hair loss (androgenetic alopecia).
• Critical raw material for the research and development of new androgen-dependent therapeutic agents.
• Reference standard for analytical testing and quality control in pharmaceutical laboratories.
• Used in clinical studies and pharmacological research investigating 5α-reductase inhibition.
• Intermediate in the synthesis of more complex steroid-based pharmaceutical compounds.

Basic Information

Product Name	Dutasteride
CAS No.	164656-23-9
Molecular Formula	C27H30F6N2O2
Molecular Weight	528.53 g/mol
Synonyms	GG745; GI198745; Avodart; Duagen; (5α,17β)-N-{2,5 Bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide; 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5α,17β)-; Dutasterida (Spanish); Dutasteridum (Latin)
EINECS	Contact for details

Quality Control

Our Dutasteride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets high-purity pharmacopeial standards. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with specified specifications. Our commitment to cGMP principles ensures reliability for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.