Description

Mirabegron CAS NO 223673-61-8 is a potent and selective β-3 adrenergic receptor agonist. This compound is of significant commercial and therapeutic importance as the active pharmaceutical ingredient (API) in medications for the treatment of overactive bladder (OAB). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of urological therapeutics and novel drug formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for overactive bladder syndrome.
• Drug Formulation R&D: Used in research to develop new dosage forms, such as extended-release tablets or combination therapies.
• Clinical Research Material: Serves as a reference standard or raw material in clinical trials and pharmacological studies.
• Biochemical Research: Employed in vitro and in vivo studies to investigate β-3 adrenergic receptor function and signaling pathways.
• Generic Drug Manufacturing: Critical for companies producing bioequivalent generic versions of branded mirabegron products.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for commercial-scale API production.

Basic Information

Product Name	Mirabegron
CAS No.	223673-61-8
Molecular Formula	C21H24N4O2S
Molecular Weight	396.51 g/mol
Synonyms	YM-178; Betmiga (brand name); Myrbetriq (brand name); 2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide; (R)-2-(2-Amino-4-thiazolyl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide; 4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]-N-(2-amino-1,3-thiazol-4-ylmethyl)benzamide
EINECS	Contact for details

Quality Control

Our Mirabegron is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with ICH guidelines and relevant pharmacopeial standards for active pharmaceutical ingredients. A comprehensive Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profiles (including specified and unspecified impurities) is provided with each batch to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unspecified impurity: ≤ 0.10% Total impurities: ≤ 1.0%
Optical Rotation	Specific range provided per grade
Particle Size Distribution	Available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.