Description

n-(8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2-Oxo-3H-Benzoimidazole-1-Carboxamide is a high-purity, complex heterocyclic compound that serves as a critical intermediate in advanced pharmaceutical synthesis. Its unique molecular architecture, featuring a fused benzoimidazole and a tropane-derived azabicyclic system, makes it a valuable building block for medicinal chemistry research and development. This compound is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and receptor-targeted drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Employed in pharmacological assays to study specific biological pathways and receptor interactions.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	n-(8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2-Oxo-3H-Benzoimidazole-1-Carboxamide
CAS No.	127618-28-4
Molecular Formula	C16H20N4O2
Molecular Weight	300.36 g/mol
Synonyms	1-[(8-Methyl-8-azabicyclo[3.2.1]oct-3-yl)carbamoyl]-1,3-dihydro-2H-benzimidazol-2-one; 2-Oxo-1,3-dihydrobenzimidazole-1-carboxylic acid (8-methyl-8-azabicyclo[3.2.1]oct-3-yl)amide; 1H-Benzimidazole-1-carboxamide, N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1,3-dihydro-2-oxo-; 8-Methyl-3-[(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino-8-azabicyclo[3.2.1]octane; Tropane-benzoimidazolone derivative
EINECS	Contact for details

Quality Control

Our n-(8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl)-2-Oxo-3H-Benzoimidazole-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.