Description

Mesna CAS NO 19767-45-4 is a synthetic organosulfur compound primarily recognized for its role as a detoxifying agent. It is a critical pharmaceutical intermediate and active ingredient valued for its protective properties against specific toxicities. This product is essential for manufacturers in the pharmaceutical industry, particularly in the production of chemoprotective medications and specialized therapeutic formulations. Its reliable quality and consistent performance make it a key component in advanced drug development and manufacturing processes.

Application

• Pharmaceutical Active Ingredient (API): Primary use as a detoxifying agent in chemoprotective medications to prevent urotoxicity caused by certain chemotherapeutic drugs like ifosfamide and cyclophosphamide.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex therapeutic molecules and prodrugs.
• Mucolytic Agent: Used in formulations designed to break down disulfide bonds in mucus proteins, aiding in the management of respiratory conditions.
• Research & Development: Utilized in biochemical and pharmacological research studies focusing on thiol chemistry, antioxidant mechanisms, and cytoprotection.
• Specialty Chemical Synthesis: Acts as a sulfur donor or reducing agent in organic synthesis for specialized fine chemicals.

Basic Information

Product Name	Mesna
CAS No.	19767-45-4
Molecular Formula	C2H5NaO3S2
Molecular Weight	164.18 g/mol
Synonyms	Mesna; Sodium 2-mercaptoethanesulfonate; Uromitexan; Mistabron; Mucofluid; 2-Mercaptoethanesulfonic acid sodium salt; Mesnum; Sodium mercaptoethanesulfonate
EINECS	243-297-9

Quality Control

Our Mesna is manufactured under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical applications. We offer grades compliant with major pharmacopoeial standards, including USP and EP. Every batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identification. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
pH (5% solution)	4.5 - 6.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.