Description

Alfuzosin CAS NO 19216-53-6 is a selective α-1 adrenergic receptor antagonist. This compound is of significant commercial and therapeutic importance as the active pharmaceutical ingredient (API) in medications used to treat the symptoms of benign prostatic hyperplasia (BPH). It is a critical raw material for pharmaceutical manufacturers and research institutions globally. The high-purity material is essential for ensuring the efficacy and safety of the final drug product.

Application

• Primary use as the Active Pharmaceutical Ingredient (API) in the manufacture of prescription medications for benign prostatic hyperplasia (BPH).
• Utilized in pharmaceutical research and development for studying α-adrenergic receptor pharmacology.
• Key intermediate or reference standard in the analytical testing and quality control of finished pharmaceutical products.
• Used in formulation development for controlled-release and immediate-release oral dosage forms.
• Serves as a critical material in regulatory submissions and stability studies for new drug applications (NDA/ANDA).

Basic Information

Product Name	Alfuzosin
CAS No.	19216-53-6
Molecular Formula	C19H27N5O4
Molecular Weight	389.45 g/mol
Synonyms	Alfuzosin Hydrochloride; SL 77.0499-10; N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide; Xatral; Uroxatral; Alfuprost; Alfuzosinum; Alfuzosini
EINECS	Contact for details

Quality Control

Our Alfuzosin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines and current Good Manufacturing Practices (cGMP). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for assay, related substances, residual solvents, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: NMT 0.5% Total impurities: NMT 2.0%
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.