Description

Rifametane CAS NO 94168-98-6 is a synthetic chemical compound belonging to the rifamycin class of antibiotics, specifically a derivative of rifampicin. It serves as a crucial intermediate in the research and development of novel antimicrobial agents, offering a pathway to create more potent or targeted therapeutic molecules. This high-purity intermediate is essential for pharmaceutical manufacturers and research institutions focused on combating drug-resistant bacterial infections and developing next-generation antibiotic therapies.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of advanced rifamycin-based antibiotics.
• Antimicrobial Research: Used in laboratory settings to study structure-activity relationships (SAR) and develop new compounds against resistant bacterial strains like MRSA and tuberculosis.
• Active Pharmaceutical Ingredient (API) Synthesis: A critical precursor in the multi-step manufacturing process of final antibiotic drug substances.
• Biochemical Research: Employed as a tool compound to investigate bacterial RNA polymerase inhibition mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Rifametane
CAS No.	94168-98-6
Molecular Formula	C44H60N4O12
Molecular Weight	837.0 g/mol
Synonyms	Rifametane; Rifampicin derivative; Rifamycin SV derivative; 25-Deacetylrifampicin; 3-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin; Rifampicin quinone; Antibiotic CGP 4832; L 510
EINECS	Contact for details

Quality Control

Our Rifametane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent internal specifications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange-red to brownish-red crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.