Description

1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine Maleate is a high-purity organic salt compound, recognized for its role as a key pharmaceutical intermediate. Its value lies in providing a reliable and consistent building block for complex synthesis, ensuring downstream product quality and process efficiency. This material is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targeted therapies.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates with potential psychotropic or neurological activity.
• Fine Chemical Synthesis: Serves as a specialized precursor in multi-step organic syntheses requiring complex heterocyclic frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine Maleate
CAS No.	94158-34-6
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	Mirtazapine Maleate; 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine Maleate; 6-Azamianserin Maleate; Org 3770 Maleate; Remeron Maleate; 2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine Maleate
EINECS	Contact for details

Quality Control

Our production of 1,2,3,4,10,14B-Hexahydro-2-Methyldibenzo[C,F]Pyrazino[1,2-A]Azepine Maleate adheres to stringent quality management protocols. Each batch is fully characterized and tested to ensure it meets exacting purity and identity specifications suitable for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.