Description

Dextrorphan D-Tartrate is the dextrorotatory enantiomer of levorphanol, a potent NMDA receptor antagonist. This high-purity chiral intermediate is critical for pharmaceutical research and development, particularly in the study of neurological pathways and receptor mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) active agents and analytical reference standards.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in drug manufacturing.
• Neurological Research: Serves as a key tool compound in preclinical studies investigating NMDA receptor function and neuropharmacology.
• Active Pharmaceutical Ingredient (API) Intermediate: A critical chiral building block in the synthetic pathway for specialized CNS-targeting pharmaceuticals.
• Metabolite Studies: Employed in research to understand the metabolism and pharmacokinetics of related opioid and antitussive agents.
• Analytical Chemistry: Used in HPLC and LC-MS methods as a separation marker or for calibrating chiral analytical columns.

Basic Information

Product Name	Dextrorphan D-Tartrate
CAS No.	143-98-6
Molecular Formula	C₁₇H₂₃NO • C₄H₆O₆
Molecular Weight	443.46 g/mol
Synonyms	Dextrorphan Tartrate; (+)-3-Hydroxy-N-methylmorphinan D-Tartrate; Dextrorphan Acid Tartrate; (9α,13α,14α)-3-Hydroxy-17-methylmorphinan D-Tartrate; NSC 82116; d-3-Hydroxy-N-methylmorphinan Tartrate; Dextrorphan (D-Tartrate)
EINECS	205-618-5

Quality Control

Our Dextrorphan D-Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.