Description

Metergoline is a high-purity ergot alkaloid derivative with significant pharmacological activity. This compound is valued in research and development for its potent and selective serotonin (5-HT) receptor antagonist properties. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on neuroscientific and endocrine studies.

Application

• Pharmaceutical Research & Development: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the study of serotoninergic systems.
• Neuropharmacology Studies: Used in preclinical research to investigate the role of 5-HT receptors in various physiological and behavioral processes.
• Endocrine Research: Employed in studies exploring the modulation of prolactin secretion due to its dopaminergic activity.
• Chemical Synthesis: Serves as a sophisticated building block for the synthesis of novel ergot-based compounds and potential therapeutics.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related substances.

Basic Information

Product Name	Metergoline
CAS No.	17692-51-2
Molecular Formula	C₂₅H₂₉N₃O₅
Molecular Weight	451.52 g/mol
Synonyms	Metergoline; 1-Methyl-8β-(carbobenzyloxyaminomethyl)-10α-ergoline; Liserdol; Metergolina; Fiume; Contralac; 1-Methyldihydrolysergamine-8β-carboxylic acid benzylamide; 8β-[(Benzyloxycarbonyl)amino]methyl]-1,6-dimethyl-10α-ergoline
EINECS	Contact for details

Quality Control

Our Metergoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.