Description

Scopolamine Hydrobromide is a high-purity, pharmaceutically active alkaloid salt derived from plants of the Solanaceae family. This compound is critical for its potent anticholinergic and antiemetic properties, making it a key intermediate in the synthesis of advanced therapeutic agents. It is primarily sought by manufacturers in the pharmaceutical, biotechnology, and advanced research sectors for developing treatments for motion sickness, postoperative nausea, and other neurological conditions.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of injectable and transdermal medications for nausea, vomiting, and motion sickness control.
• Neurological Research: Used as a standard muscarinic acetylcholine receptor antagonist in preclinical studies investigating cholinergic pathways and CNS disorders.
• Veterinary Medicine: Employed in veterinary pharmaceuticals for its sedative and antiemetic effects in animals.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.
• Transdermal Patch Manufacturing: A vital raw material in the production of long-acting anti-motion sickness patches.
• Pre-anesthetic Medication: Used in formulations to reduce salivary and bronchial secretions before surgery.

Basic Information

Product Name	Scopolamine Hydrobromide
CAS No.	114-49-8
Molecular Formula	C17H21NO4 • HBr
Molecular Weight	384.27 g/mol
Synonyms	Hyoscine Hydrobromide; (-)-Scopolamine Hydrobromide; Scopolamine HBr; 6β,7β-Epoxy-3α-tropanyl S-(-)-tropate Hydrobromide; L-Hyoscine Hydrobromide; Transderm-Scop (API); Buscopan (related compound); Atroquin (related compound)
EINECS	204-050-2

Quality Control

Our Scopolamine Hydrobromide is manufactured under strict quality management systems. Each batch is tested to meet stringent specifications for identity, purity, and potency, aligning with pharmacopeial standards. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological attributes is provided with every shipment to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-24° to -28° (c = 5 in H2O)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.