Description

2-Chloro-5-Ethyl-5,9,10,14B-Tetrahydroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One is a high-purity, complex heterocyclic organic compound belonging to the benzodiazepine class, serving as a critical advanced intermediate in pharmaceutical research and development. Its intricate fused-ring structure makes it a valuable scaffold for synthesizing novel therapeutic agents targeting the central nervous system. This compound is essential for medicinal chemists and R&D laboratories in the pharmaceutical and biotechnology sectors focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-derived active pharmaceutical ingredients (APIs) and potential drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore new therapeutic pathways in CNS disorders.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Employed in the early-stage development of new chemical entities for pharmacological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis and pharmacology.

Basic Information

Product Name	2-Chloro-5-Ethyl-5,9,10,14B-Tetrahydroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One
CAS No.	10159-05-4
Molecular Formula	C19H19ClN2O
Molecular Weight	326.82 g/mol
Synonyms	2-Chloro-5-ethyl-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one; 2-Chloro-5-ethyl-5,9,10,14b-tetrahydroisoquinolino[2,1-d][1,4]benzodiazepin-6-one; 10159-05-4; Isoquino[2,1-d][1,4]benzodiazepin-6(7H)-one, 2-chloro-5-ethyl-5,9,10,14b-tetrahydro-; 2-Chloro-5-ethyl-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6-one; 5-Ethyl-2-chloro-5,9,10,14b-tetrahydro-6H-isoquino[2,1-d][1,4]benzodiazepin-6-one
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Ethyl-5,9,10,14B-Tetrahydroisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.