Description

4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6-[[5-(Acetylamino)-5-Carboxy-1-Oxopentyl]Amino]-3,3-Dimethyl-7-Oxo-, [2S-[2α,5α,6β(R*)]]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic β-lactam structure. This compound is of significant value for its role as a key synthetic precursor in the development of novel antibiotics and other active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis and process development of next-generation antimicrobial agents.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel β-lactam antibiotics and other specialized APIs.
• Antimicrobial Research: Used in medicinal chemistry research for developing new compounds with activity against resistant bacterial strains.
• Process Chemistry: Serves as a key starting material or intermediate in scale-up and optimization of synthetic routes for complex molecules.
• Biochemical Studies: Utilized in studies investigating enzyme inhibition, particularly those involving bacterial cell wall synthesis.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid, 6-[[5-(Acetylamino)-5-Carboxy-1-Oxopentyl]Amino]-3,3-Dimethyl-7-Oxo-, [2S-[2α,5α,6β(R*)]]- (9Ci)
CAS No.	94040-19-4
Molecular Formula	C16H23N3O7S
Molecular Weight	401.44 g/mol
Synonyms	(2S,5R,6R)-6-[(R)-2-Acetamido-2-carboxyethylthioacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-[[(5S)-5-Acetamido-5-carboxy-1-oxopentyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; A derivative of 6-APA (6-Aminopenicillanic Acid); Penicillin G derivative intermediate; β-lactam intermediate; CAS 94040-19-4
EINECS	Contact for details

Quality Control

Our 4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.