Description

2',3'-Dideoxycytidine 5'-Triphosphate Lithium Salt is a chemically modified nucleotide triphosphate analog, specifically engineered for research and diagnostic applications. This compound is critical for enzymatic studies, particularly those involving DNA polymerases, where it acts as a chain terminator. It is primarily utilized by researchers and manufacturers in the fields of molecular biology, virology, and next-generation sequencing (NGS) for specialized assay development and mechanistic investigations.

Application

• Molecular Biology Research: Used as a substrate analog in enzymatic studies of reverse transcriptase and other DNA polymerases to investigate reaction mechanisms and inhibition.
• Virology & Antiviral Drug Development: Serves as a key biochemical tool in the study of nucleoside reverse transcriptase inhibitors (NRTIs) for HIV and other viral research.
• Next-Generation Sequencing (NGS): Employed in specialized sequencing methodologies that require controlled termination of DNA strand elongation.
• Diagnostic Assay Development: Integral to the formulation of proprietary kits for pathogen detection and genetic analysis that rely on chain termination principles.
• Biochemical Reagent Manufacturing: A high-purity raw material for producing master mixes and specialized enzymatic reagents for life science research.

Basic Information

Product Name	2',3'-Dideoxycytidine 5'-Triphosphate Lithium Salt
CAS No.	93939-77-6
Molecular Formula	C9H13Li3N3O12P3
Molecular Weight	491.02 g/mol (Lithium salt form)
Synonyms	ddCTP Lithium Salt; 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt; 2',3'-ddCTP; ddCTP; Dideoxycytidine triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 2',3'-dideoxy-, trilithium salt; 2',3'-Dideoxy-CTP; NSC 606172
EINECS	Contact for details

Quality Control

Every batch of 2',3'-Dideoxycytidine 5'-Triphosphate Lithium Salt is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency suitable for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Endotoxin	< 10 EU/mg (if specified)
Biological Activity	Suitable for enzymatic incorporation

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.