Description

2',3'-Dideoxyguanosine 5'-Triphosphate*Lithium 10 Mm is a chemically modified nucleotide triphosphate analog, supplied as a ready-to-use 10 mM aqueous solution with lithium counterions. This product is critical for biochemical research where it acts as a chain terminator, enabling precise studies on nucleic acid synthesis and enzyme mechanisms. It is an essential reagent for molecular biologists and pharmaceutical researchers focused on virology, enzymology, and the development of nucleotide-based therapeutics.

Application

• DNA Sequencing & Analysis: Used as a chain-terminating substrate in Sanger sequencing and related enzymatic nucleic acid synthesis studies.
• Enzyme Kinetics & Mechanism Studies: Serves as a substrate or inhibitor to investigate the activity and specificity of DNA polymerases, reverse transcriptases, and other nucleic acid-processing enzymes.
• Antiviral Research: Investigated for its potential role in studying nucleoside analog drugs that target viral replication, particularly for retroviruses.
• Biochemical Assay Development: Utilized in the formulation of specialized reaction mixes for diagnostic kits and high-throughput screening assays.
• Metabolic Pathway Research: Applied in studies of nucleotide metabolism and the biochemical effects of modified nucleotides within cellular systems.

Basic Information

Product Name	2',3'-Dideoxyguanosine 5'-Triphosphate*Lithium 10 Mm
CAS No.	93939-69-6
Molecular Formula	C10H15Li4N5O12P3 (for lithium salt)
Molecular Weight	Contact for details
Synonyms	2',3'-Dideoxy-GTP lithium salt; ddGTP Li salt; 2',3'-Dideoxyguanosine-5'-triphosphate lithium salt; 2',3'-ddGTP (lithium); Guanosine, 2',3'-dideoxy-, 5'-(tetrahydrogen triphosphate), lithium salt; 5'-Triphosphoric acid, 2',3'-dideoxyguanosine, lithium salt; ddGTP*Li; 2',3'-Dideoxyguanosine 5'-(tetrahydrogen triphosphate) lithium salt
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxyguanosine 5'-Triphosphate*Lithium 10 Mm solution is manufactured under stringent controls to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is analyzed to confirm identity, purity, concentration, and the absence of contaminating nucleases. A comprehensive Certificate of Analysis (COA) detailing HPLC purity, pH, osmolarity, and sterility testing (where applicable) is provided to guarantee it meets the exacting standards required for molecular biology and biochemical research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. Under these recommended conditions, the product is stable for extended periods.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Concentration	10 mM ± 5%
pH	6.5 - 7.5
Purity (HPLC)	≥ 95%
Identification (HPLC/MS)	Conforms to reference standard
Endotoxin Level	< 0.1 EU/µmol (if specified)
Nuclease Activity	Not detected

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.