Description

6-(2-(3-(2-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid is a sophisticated β-lactam derivative, representing a key advanced intermediate in the synthesis of novel penicillins and cephalosporins. Its complex structure, featuring a penicillanic acid core modified with a chlorinated dihydroxybenzoyl-ureido-phenylacetamido side chain, is engineered to impart enhanced biological activity and resistance to β-lactamase degradation. This compound is of critical importance to pharmaceutical R&D and manufacturing teams focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of novel broad-spectrum penicillin and cephalosporin antibiotics.
• Antibacterial Drug Discovery: Serves as a key scaffold in medicinal chemistry for designing and testing new β-lactam compounds with improved efficacy.
• Research & Development: Utilized in academic and industrial laboratories for studying structure-activity relationships (SAR) within the β-lactam antibiotic class.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for advanced antibiotic active pharmaceutical ingredients (APIs).
• Combinatorial Chemistry: Can be used as a versatile intermediate for generating libraries of related compounds for high-throughput screening.

Basic Information

Product Name	6-(2-(3-(2-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid
CAS No.	92773-65-4
Molecular Formula	C30H29ClN4O9S
Molecular Weight	657.09 g/mol
Synonyms	6-[(2-{3-[(2-Chloro-3,4-dihydroxybenzoyl)-3-(3-hydroxypropyl)ureido]-2-phenylacetamido})penicillanic acid; (2S,5R,6R)-6-({(2R)-2-[(3-{[(2-Chloro-3,4-dihydroxybenzoyl)-3-(3-hydroxypropyl)carbamoyl]amino})-2-phenylacetamido]penicillanic acid; Penicillanic acid derivative 92773-65-4; Advanced penicillin intermediate; β-Lactam intermediate CAS 92773-65-4
EINECS	Contact for details

Quality Control

Our 6-(2-(3-(2-Chloro-3,4-Dihydroxybenzoyl)-3-(3-Hydroxypropyl)-1-Ureido)-2-Phenylacetamido)Penicillanic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.