Description

(5S,6S)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol is a high-purity, stereochemically defined dihydrodiol derivative of a polycyclic aromatic hydrocarbon (PAH). This compound is of significant value as a critical reference standard and advanced synthetic intermediate in research focused on metabolic pathways and toxicity studies. It is primarily required by pharmaceutical R&D laboratories, toxicology research institutions, and academic departments specializing in chemical carcinogenesis and environmental science.

Application

• Metabolic Pathway Research: Used as a precise biochemical tool to study the metabolic activation and detoxification pathways of polycyclic aromatic hydrocarbons (PAHs).
• Toxicology and Carcinogenicity Studies: Serves as a key intermediate or standard in investigating the mechanisms of PAH-induced DNA adduct formation and cellular toxicity.
• Analytical Reference Standard: Essential for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) in environmental and biological monitoring for PAH metabolites.
• Pharmaceutical Intermediate: Acts as a specialized building block in the synthesis of more complex molecules for pharmacological research.
• Biochemical Assay Development: Employed in the development of enzymatic assays to study epoxide hydrolase and other relevant enzyme activities.

Basic Information

Product Name	(5S,6S)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol
CAS No.	92693-64-6
Molecular Formula	C₂₂H₂₀O₂
Molecular Weight	316.40 g/mol
Synonyms	(5S,6S)-7,12-Dimethylbenz[a]anthracene-5,6-diol; (5S,6S)-Dihydro-7,12-dimethylbenz[a]anthracene-5,6-diol; (5S,6S)-5,6-Dihydroxy-5,6-dihydro-7,12-dimethylbenz[a]anthracene; (5S,6S)-7,12-DMBA-5,6-diol; (+)-(5S,6S)-Dihydrodiol of 7,12-Dimethylbenz[a]anthracene; Stereoisomer of DMBA dihydrodiol
EINECS	Contact for details

Quality Control

Our (5S,6S)-5,6-Dihydro-7,12-Dimethylbenz[A]Anthracene-5,6-Diol is manufactured under controlled conditions to ensure high stereochemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and related substances is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (5S,6S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.