Description

Frumil CAS NO 92522-90-2 is a high-purity active pharmaceutical ingredient (API) and chemical intermediate. This compound is critical for ensuring the efficacy and consistency of final pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical industry for research, development, and production of specific therapeutic agents.

Application

• Pharmaceutical API: Serves as a key active ingredient in the formulation of prescription medications.
• Chemical Synthesis Intermediate: Used in multi-step organic synthesis to build more complex molecular structures in R&D and production.
• Research & Development: Employed in academic and industrial laboratories for pharmacological studies and new drug discovery.
• Reference Standard: Utilized as a high-purity standard for analytical method development, validation, and quality control testing.
• Preclinical Studies: Applied in animal testing and other preclinical research to evaluate pharmacokinetics and toxicity.

Basic Information

Product Name	Frumil
CAS No.	92522-90-2
Molecular Formula	C16H19FN4O3
Molecular Weight	334.35 g/mol
Synonyms	Frumil; Amiloride Hydrochloride Hydrochlorothiazide; Amiloride HCl - HCTZ; 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride - 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Amiloride HCL and Hydrochlorothiazide; Amiloride and Hydrochlorothiazide Combination; NSC-77625; Combination Diuretic Frumil
EINECS	Contact for details

Quality Control

Our Frumil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC and IR spectroscopy, to ensure it meets high-purity pharmacopeial standards. Certificates of Analysis (COA) documenting full compliance with specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.