Description

n-tert-Butyl-4-(trifluoromethyl)benzamide is a specialized benzamide derivative featuring a trifluoromethyl group and a tert-butyl amide moiety. This compound is valued for its unique structural properties, which make it a versatile and critical building block in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the metabolic stability imparted by the trifluoromethyl group.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides, where the tert-butyl and benzamide structures contribute to biological activity and selectivity.
• Ligand and Catalyst Development: Acts as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Incorporated into polymers and advanced materials to modify thermal stability, solubility, and surface properties.
• Chemical Biology Probe: Utilized in the design of molecular probes for studying enzyme function and protein-ligand interactions.

Basic Information

Product Name	n-tert-Butyl-4-(trifluoromethyl)benzamide
CAS No.	91888-96-9
Molecular Formula	C₁₂H₁₄F₃NO
Molecular Weight	245.24 g/mol
Synonyms	4-(Trifluoromethyl)-N-(tert-butyl)benzamide; N-(tert-Butyl)-4-(trifluoromethyl)benzamide; N-tert-Butyl-α,α,α-trifluoro-p-toluamide; Benzamide, N-(1,1-dimethylethyl)-4-(trifluoromethyl)-; 91888-96-9; p-(Trifluoromethyl)-N-tert-butylbenzamide; N-(tert-Butyl)-4-trifluoromethylbenzamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-4-(trifluoromethyl)benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed specifications are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.