Description

Poly(Deoxyguanylic-5-Azadeoxycytidylic Acid) is a synthetic polynucleotide analog, specifically a copolymer of deoxyguanylic acid and 5-azadeoxycytidylic acid. This compound is of significant interest in advanced biochemical and pharmaceutical research due to its unique structural properties and potential to interact with nucleic acid systems. It is primarily utilized by research institutions and biotechnology companies engaged in the development of novel therapeutic agents, diagnostic tools, and fundamental studies in molecular biology and genetics.

Application

• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies involving polymerases, nucleases, and other nucleic acid-modifying enzymes.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the research and development of antiviral and anticancer therapies that target DNA replication and repair mechanisms.
• Molecular Biology: Employed in studies of nucleic acid structure, stability, and hybridization, particularly where modified bases are required to probe specific interactions.
• Diagnostic Probe Development: Potential use in the design of specialized probes for detecting specific genetic sequences or mutations, leveraging its altered base-pairing properties.
• Antisense & Gene Silencing Research: Investigated for its utility in antisense oligonucleotide strategies aimed at regulating gene expression.

Basic Information

Product Name	Poly(Deoxyguanylic-5-Azadeoxycytidylic Acid)
CAS No.	91796-04-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(dG-5-aza-dC); Poly(deoxyguanylate-5-azadeoxycytidylate); 5-Aza-dC/dG Copolymer; Poly(dG-dC[5-aza]); Azacytidine-deoxyguanosine Copolymer; Polynucleotide Analog 91796-04-2; dG-5-aza-dC Polymer
EINECS	Contact for details

Quality Control

Our Poly(Deoxyguanylic-5-Azadeoxycytidylic Acid) is produced under stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as base composition, chain length distribution, and purity is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95% (by total nucleotide content)
Base Ratio (dG:5-aza-dC)	As per customer requirement
Water Content (KF)	≤ 5.0%
Solubility	Soluble in aqueous buffers, DMSO (limited)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.