Description

Norvancomycin is a glycopeptide antibiotic structurally related to vancomycin, primarily used in pharmaceutical research and development. Its significance lies in its potent activity against Gram-positive bacteria, including strains resistant to other antibiotics, making it a critical compound for developing new antimicrobial therapies. This product is essential for pharmaceutical manufacturers, research institutions, and laboratories focused on antibiotic development, microbiology studies, and quality control of related pharmaceutical products.

Application

• Pharmaceutical Active Ingredient (API): Serves as a key raw material in the formulation of injectable antibiotic drugs.
• Microbiological Research: Used in laboratory studies to investigate mechanisms of action against resistant bacterial strains like MRSA (Methicillin-resistant *Staphylococcus aureus*).
• Reference Standard: Employed as a high-purity analytical standard in HPLC and other chromatographic methods for quality control and assay development.
• Antibiotic Susceptibility Testing: Utilized in preparing discs or solutions for in-vitro antimicrobial susceptibility testing (AST).
• Biochemical Studies: Applied in research exploring bacterial cell wall synthesis and the inhibition of peptidoglycan formation.

Basic Information

Product Name	Norvancomycin
CAS No.	91700-98-0
Molecular Formula	C66H75Cl2N9O24
Molecular Weight	1449.2 g/mol
Synonyms	N-Demethylvancomycin; Demethylvancomycin; Antibiotic A 51568A; Norvancomycin Hydrochloride; Vancomycin B; (1S,2R,18R,19R,22S,25R,28R,40S)-48-[[2-O-(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-22-(carbamoylmethyl)-5,47-dichloro-2,18,32,35,37-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8,10,12(50),14,16,29(49),30,32,34,36,38,45,47-pentadecaene-40-carboxylic acid
EINECS	Contact for details

Quality Control

Our Norvancomycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) are provided, detailing key parameters such as assay, purity, and identification. We adhere to relevant guidelines for the production of active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Microbial Limits	Meets standard requirements for non-sterile API

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.