Description

4-Bromo-2-Fluoro-5-Hydroxybenzoic Acid is a high-purity halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromo and fluoro substituents contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating specialized aromatic cores in electronic and photonic materials.
• Organic Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: The hydroxybenzoic acid scaffold is utilized to create novel fluorophores and molecular probes for analytical chemistry.
• Custom Chemical & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, multi-functional intermediates.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Hydroxybenzoic Acid
CAS No.	91659-18-6
Molecular Formula	C7H4BrFO3
Molecular Weight	235.01 g/mol
Synonyms	5-Hydroxy-4-bromo-2-fluorobenzoic Acid; 2-Fluoro-5-hydroxy-4-bromobenzoic Acid; 4-Bromo-2-fluoro-5-hydroxybenzoic acid; Benzoic acid, 4-bromo-2-fluoro-5-hydroxy-; 91659-18-6
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.