Description

Ropinirole CAS NO 91374-21-9 is a non-ergoline dopamine agonist API (Active Pharmaceutical Ingredient) of high pharmaceutical importance. It is primarily valued for its efficacy in modulating dopamine receptors within the central nervous system. This compound is essential for manufacturers in the pharmaceutical industry developing treatments for neurological disorders, most notably Parkinson's disease and Restless Legs Syndrome (RLS).

Application

• Pharmaceutical API: Primary active ingredient in finished dosage forms for the treatment of Parkinson's disease.
• Neurological Therapeutics: Key component in medications for managing symptoms of Restless Legs Syndrome (RLS).
• Generic Drug Manufacturing: Sourcing for the production of generic ropinirole hydrochloride tablets.
• Clinical Research: Used as a reference standard or raw material in preclinical and clinical studies for new neurological treatments.
• Formulation Development: Serves as the core active component during the R&D of extended-release or novel drug delivery systems.

Basic Information

Product Name	Ropinirole
CAS No.	91374-21-9
Molecular Formula	C16H24N2O
Molecular Weight	260.38 g/mol
Synonyms	4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one; ReQuip; Adartrel; SKF-101468; Ropinirole Hydrochloride (salt form); Dopamine D2 Receptor Agonist; Non-ergot Dopamine Agonist
EINECS	Contact for details

Quality Control

Our Ropinirole is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, with specifications typically aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.