Description

Ristocetin A (Sulfate) is a glycopeptide antibiotic complex derived from *Amycolatopsis lurida*, primarily known for its sulfate salt form. This compound is of significant value in biochemical and pharmaceutical research due to its specific mechanism of action, which involves binding to the D-Ala-D-Ala terminus of peptidoglycan precursors, inhibiting bacterial cell wall synthesis. It is a critical reagent for researchers and quality control laboratories in the pharmaceutical and diagnostic industries, particularly for studying antibiotic mechanisms and for use in coagulation assays.

Application

• Biochemical Research: Used as a tool compound to study the mechanism of action of glycopeptide antibiotics and bacterial cell wall biosynthesis.
• Pharmaceutical Development: Serves as a reference standard in the research and development of novel antibacterial agents.
• Diagnostic Reagent: Employed in clinical hematology for platelet aggregation studies and as a reagent in certain coagulation factor assays.
• Microbiology: Used in susceptibility testing and research on antibiotic-resistant bacteria, particularly vancomycin-resistant strains.
• Quality Control (QC): Acts as a certified reference material (CRM) for the assay and purity testing of related pharmaceutical products.

Basic Information

Product Name	Ristocetin A (Sulfate)
CAS No.	90831-71-3
Molecular Formula	C95H105Cl2N9O36S • xH2SO4
Molecular Weight	~2067.9 (base) + sulfate
Synonyms	Ristocetin A Sulfate; Ristomycin A Sulfate; Antibiotic A 4696 Sulfate; Ristocetin Sulfate; Spontin; Riston; Ristocetin Component A Sulfate; Ristocetin A, sulfate salt
EINECS	Contact for details

Quality Control

Our Ristocetin A (Sulfate) is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and identification data. We adhere to relevant industry guidelines to support our customers' compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0 %
pH (1% solution)	3.0 - 5.0
Specific Rotation	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.