Description

2-(4-Fluorophenyl)Butanoic Acid is a versatile fluorinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its core value lies in providing a chiral center and a reactive carboxyl group adjacent to a fluorinated phenyl ring, enabling the construction of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Synthesis Building Block: Employed in asymmetric synthesis, peptide mimetics, and the creation of complex organic frameworks in R&D settings.
• Chemical Research: Utilized in academic and industrial laboratories for method development and exploring new fluorination chemistry pathways.

Basic Information

Product Name	2-(4-Fluorophenyl)Butanoic Acid
CAS No.	90794-16-4
Molecular Formula	C₁₀H₁₁FO₂
Molecular Weight	182.19 g/mol
Synonyms	2-(4-Fluorophenyl)butyric acid; (±)-2-(4-Fluorophenyl)butanoic acid; DL-2-(p-Fluorophenyl)butyric acid; 4-Fluoro-α-ethylbenzenacetic acid; p-Fluoro-α-ethylphenylacetic acid; α-Ethyl-4-fluorobenzenacetic acid; 2-(4-Fluorophenyl)butanoic acid; Benzenacetic acid, α-ethyl-4-fluoro-
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Butanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with every shipment. We support cGMP and ISO standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Melting Point	~85-90°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.