Description

Xaliproden Hydrochloride is a high-purity pharmaceutical intermediate and research chemical with significant therapeutic potential. This compound is primarily valued for its role in the development of neuroprotective and neurotrophic agents targeting conditions such as amyotrophic lateral sclerosis (ALS). It is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in neuroscience and neurodegenerative disease research.

Application

• Pharmaceutical Active Ingredient (API) Intermediate: A key synthetic precursor in the production of neuroprotective drug candidates.
• Neuroscience Research: Used in preclinical studies to investigate mechanisms of action related to motor neuron survival and function.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Drug Discovery & Development: Employed in high-throughput screening and structure-activity relationship (SAR) studies for novel central nervous system (CNS) therapeutics.
• Academic & Clinical Research: Utilized in university and hospital labs for studying neurodegenerative pathways and potential treatment efficacy.

Basic Information

Product Name	Xaliproden Hydrochloride
CAS No.	90494-79-4
Molecular Formula	C₁₇H₂₅N₃O₂ • HCl
Molecular Weight	339.86 g/mol (as hydrochloride salt)
Synonyms	Xaliproden HCl; SR 57746A; SR-57746; 1-[2-(2-Naphthyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride; Naphthyletrahydro-pyridine Derivative SR 57746A
EINECS	Contact for details

Quality Control

Our Xaliproden Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.