Description

Dextran Sulfate CAS NO 9042-14-2 is a sulfated polysaccharide derivative of dextran, widely recognized for its polyanionic properties and high negative charge density. This compound is essential for applications requiring selective precipitation, anticoagulant activity, or as a cofactor in biochemical assays. It serves as a critical reagent for research and industrial processes in life sciences, pharmaceuticals, and diagnostics.

Application

• Lipoprotein Precipitation: Used in clinical diagnostics for the selective precipitation of low-density lipoproteins (LDL) from serum.
• Anticoagulant Agent: Functions as an anticoagulant in blood collection tubes and certain in vitro applications.
• Virus Research: Acts as an inhibitor of virus replication and cell attachment for various enveloped viruses, including HIV.
• Cell Culture & Immunology: Employed as a stimulant for B-lymphocyte proliferation and in various cell separation techniques.
• Biochemical Assays: Serves as a cofactor for the activation of enzymes like lipoprotein lipase.
• Chromatography: Utilized in ion-exchange chromatography and as a component in affinity media.
• Pharmaceutical Excipient: Investigated for use in drug delivery systems due to its mucoadhesive properties.

Basic Information

Product Name	Dextran Sulfate
CAS No.	9042-14-2
Molecular Formula	(C6H10O5)n·x(SO3Na)
Molecular Weight	Variable (typically 5,000 - 500,000 Da)
Synonyms	Dextran Sulfate Sodium Salt; Sodium Dextran Sulfate; Dextran Sulphate; Dextran Polysulfate; Dextran Hydrogen Sulfate; DS; DSS; Dextran Sulfuric Acid Ester
EINECS	Contact for details

Quality Control

Our Dextran Sulfate is manufactured under a rigorous quality management system. Each batch is tested to ensure compliance with critical parameters such as sulfur content, molecular weight distribution, and biological activity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific application performance is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive). For long-term stability, consider storage under desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (Sulfur Content)	16.0 - 20.0 %
pH (1% solution)	5.0 - 7.5
Loss on Drying	≤ 10.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Molecular Weight (Average)	Specified Grade (e.g., 5kDa, 40kDa, 500kDa)
Biological Activity (aPTT)	Tested per batch

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.