Description

Benzoic Acid, 3-[(Trifluoromethyl)Sulfonyl]- is a high-value, multi-functional chemical intermediate distinguished by its unique combination of a benzoic acid core and a powerful trifluoromethanesulfonyl (triflyl) group. This structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs), where its electron-withdrawing properties are essential. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with enhanced stability and biological activity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethanesulfonyl group contributes to efficacy and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized in the design of activity-based probes and other tools for studying enzymatic function.

Basic Information

Product Name	Benzoic Acid, 3-[(Trifluoromethyl)Sulfonyl]-
CAS No.	952-69-2
Molecular Formula	C8H5F3O4S
Molecular Weight	254.18 g/mol
Synonyms	3-(Trifluoromethanesulfonyl)benzoic acid; m-(Triflyl)benzoic acid; Benzoic acid, m-trifluoromethanesulfonyl-; 3-Carboxybenzenesulfonyl fluoride, 1,1,1-trifluoro-; α,α,α-Trifluoro-m-sulfobenzoic acid; TFSBA; 3-Trifluoromethanesulfonylbenzoic acid
EINECS	Contact for details

Quality Control

Every batch of Benzoic Acid, 3-[(Trifluoromethyl)Sulfonyl]- is manufactured under strict quality management protocols. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.