Description

8-(3-Fluorophenyl)-8-Oxooctanoic Acid is a high-purity fluorinated aromatic keto acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals, where the fluorine atom and carboxylic acid functionality are leveraged for tuning biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the fluorophenyl moiety can enhance lipophilicity and target binding.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display technologies and organic electronics.
• Polymer Modification: Employed to introduce fluorinated aromatic side chains into polymers, improving chemical resistance, thermal stability, and surface properties.
• Chemical Research: A versatile reagent for academic and industrial research in organic synthesis, including studies on fluorination effects and new coupling methodologies.
• Peptide Mimetics & Bio-conjugation: The carboxylic acid group allows for coupling to amines, making it useful for creating fluorinated peptide analogs or diagnostic probes.

Basic Information

Product Name	8-(3-Fluorophenyl)-8-Oxooctanoic Acid
CAS No.	898765-69-0
Molecular Formula	C14H17FO3
Molecular Weight	252.28 g/mol
Synonyms	8-Oxo-8-(3-fluorophenyl)octanoic Acid; 3-Fluorobenzoylheptanoic Acid; ω-(3-Fluorobenzoyl)heptanoic Acid; 8-(3-Fluorobenzoyl)octanoic Acid; 3-Fluorophenyl 7-carboxyheptyl ketone; FPOA; 3-Fluoro-ω-benzoylheptanoic Acid; 898765-69-0
EINECS	Contact for details

Quality Control

Every batch of 8-(3-Fluorophenyl)-8-Oxooctanoic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting lot-specific results are provided with each shipment and are available upon request. We support custom synthesis to meet specific pharmacopeial (e.g., USP) or customer-defined specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.