Description

1-(2-Fluorobenzyl)Piperidine-3-Carboxylic Acid is a high-purity, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific fluorine substitution and carboxylic acid functionality are key. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology-related therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorobenzyl moiety can influence biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Can be utilized in the synthesis of advanced polymers or functionalized surfaces with specific chemical properties.

Basic Information

Product Name	1-(2-Fluorobenzyl)Piperidine-3-Carboxylic Acid
CAS No.	896046-65-4
Molecular Formula	C14H18FNO2
Molecular Weight	251.30 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]-3-piperidinecarboxylic acid; 3-Piperidinecarboxylic acid, 1-[(2-fluorophenyl)methyl]-; 1-(2-Fluorobenzyl)piperidine-3-carboxylic acid; 1-(2-Fluorobenzyl)nipecotic acid; 2-Fluorobenzyl nipecotate; Nipecotic acid, 1-(2-fluorobenzyl)-; 896046-65-4; FBPCA
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.