Description

6-Fluorobenzo[D]Isoxazole-3-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique scaffold introduces desirable pharmacological and physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides with enhanced activity and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and functional materials requiring fluorinated isoxazole motifs for specific electronic or surface properties.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and activity-based probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client-specific research programs.

Basic Information

Product Name	6-Fluorobenzo[D]Isoxazole-3-Carboxylic Acid
CAS No.	894789-43-6
Molecular Formula	C8H4FNO3
Molecular Weight	181.12 g/mol
Synonyms	6-Fluorobenzo[d]isoxazole-3-carboxylic acid; 3-Carboxy-6-fluorobenzo[d]isoxazole; 6-Fluoro-1,2-benzisoxazole-3-carboxylic acid; 6-Fluoro-benzo[d]isoxazole-3-carboxylic acid; 6-Fluorobenzoisoxazole-3-carboxylic Acid; 6-F-BIC Acid; 6-Fluorobenzisoxazole-3-carboxylic Acid; 894789-43-6
EINECS	Contact for details

Quality Control

Our 6-Fluorobenzo[D]Isoxazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and MS. Our quality commitment supports applications requiring GMP-grade starting materials and research-grade purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.