Description

5-[3-(Trifluoromethyl)Phenyl]Nicotinic Acid is a high-value, multi-functional organic building block characterized by its nicotinic acid core and trifluoromethylphenyl substituent. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its rigid, aromatic structure.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and bio-imaging applications.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]Nicotinic Acid
CAS No.	893740-46-0
Molecular Formula	C13H8F3NO2
Molecular Weight	267.21 g/mol
Synonyms	5-[3-(Trifluoromethyl)phenyl]pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 5-[3-(trifluoromethyl)phenyl]-; 5-(3-Trifluoromethylphenyl)nicotinic acid; 5-(m-Trifluoromethylphenyl)nicotinic acid; 3-Carboxy-5-(3-trifluoromethylphenyl)pyridine; Nicotinic acid, 5-[3-(trifluoromethyl)phenyl]-; 893740-46-0
EINECS	Contact for details

Quality Control

Our 5-[3-(Trifluoromethyl)Phenyl]Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.