Description

6-Chloro-2,3-Difluorophenylacetic Acid, 97% is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the chloro and difluoro substituents impart unique biological activity and metabolic stability. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl moiety enhances lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals, contributing to materials with enhanced thermal stability and optical properties.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Chloro-2,3-Difluorophenylacetic Acid, 97%
CAS No.	887585-13-9
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	2-(6-Chloro-2,3-difluorophenyl)acetic Acid; (6-Chloro-2,3-difluorophenyl)acetic Acid; 6-Chloro-2,3-difluorobenzeneacetic Acid; α-(6-Chloro-2,3-difluorophenyl)acetic Acid; 887585-13-9; 6-Chloro-2,3-difluoro-phenyl-acetic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2,3-Difluorophenylacetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and precise customer specifications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.