Description

3',4'-Difluoro-4-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity, multifunctional biphenyl derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which incorporates both a carboxylic acid and a phenolic hydroxyl group, each flanked by fluorine atoms, enabling precise structural modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require sophisticated building blocks for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the difluorinated biphenyl core contributes to enhanced biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for the synthesis of fluorinated biphenyl-based compounds used in liquid crystal displays (LCDs) and other advanced electronic materials.
• Organic Light-Emitting Diodes (OLEDs): Acts as a starting material for the creation of electron-transport or host materials in OLED devices due to its stable, conjugated structure.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a versatile scaffold for medicinal chemistry, material science, and catalysis studies.

Basic Information

Product Name	3',4'-Difluoro-4-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	887576-75-2
Molecular Formula	C13H8F2O3
Molecular Weight	250.20 g/mol
Synonyms	4'-Hydroxy-3',4-difluorobiphenyl-3-carboxylic acid; 3-(3,4-Difluoro-4'-hydroxybiphenyl-3-yl)propanoic acid (common misassignment); 3',4'-Difluoro-4-hydroxybiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 3',4'-difluoro-4-hydroxy-; 4-Hydroxy-3',4'-difluoro-1,1'-biphenyl-3-carboxylic acid; Difluorohydroxybiphenylcarboxylic Acid; DFHBCA
EINECS	Contact for details

Quality Control

Our 3',4'-Difluoro-4-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from strong acids and organic solvents to maintain stability. Keep the container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.