Description

3-Bromo-5-Fluorocinnamic Acid is a halogenated cinnamic acid derivative that serves as a versatile and high-value synthetic building block. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in medicinal chemistry, crop protection, and organic electronics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated and brominated organic semiconductors and liquid crystal compounds.
• Peptide Mimetics & Bioconjugation: The carboxylic acid group enables its use in creating peptide analogs and for bioconjugation linker chemistry.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	3-Bromo-5-Fluorocinnamic Acid
CAS No.	887268-21-5
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	(E)-3-(3-Bromo-5-fluorophenyl)acrylic acid; 3-Bromo-5-fluorocinnamic acid; (3-Bromo-5-fluorophenyl)acrylic acid; 2-Propenoic acid, 3-(3-bromo-5-fluorophenyl)-, (E)-; 3-Bromo-5-fluoro-trans-cinnamic acid; trans-3-(3-Bromo-5-fluorophenyl)acrylic acid; 3-Br-5-F-CA
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluorocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.