Description

Methyl 3-Cyano-5-Fluorobenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a cyano and a fluorine substituent, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, receptor modulators, and other fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electronic properties and device performance.
• Functional Polymer Monomer: Employed in the development of specialty polymers and coatings, where the cyano and ester groups offer sites for further chemical modification and cross-linking.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new fluorination chemistry, cross-coupling reactions, and heterocyclic compound synthesis.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	Methyl 3-Cyano-5-Fluorobenzoate
CAS No.	886732-29-2
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	3-Cyano-5-fluorobenzoic acid methyl ester; Methyl 5-fluoro-3-cyanobenzoate; 5-Fluoro-3-cyanobenzoic acid methyl ester; Benzoic acid, 3-cyano-5-fluoro-, methyl ester; Methyl 3-cyano-5-fluorobenzoate; 886732-29-2; Methyl 5-fluoro-3-cyanobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Cyano-5-Fluorobenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.