Description

4-Chloro-3-(Trifluoromethoxy)Cinnamic Acid is a high-value, multi-functional chemical intermediate characterized by its unique trifluoromethoxy and cinnamic acid backbone. This compound matters for its role in introducing specific steric and electronic properties into target molecules, which is critical for fine-tuning biological activity and material characteristics. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring advanced organic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for introducing the lipophilic trifluoromethoxy group to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where its structural motifs can contribute to enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced organic electronic materials, contributing to the molecular design of charge-transport layers and emissive compounds.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific properties like hydrophobicity or UV stability into specialty polymers.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethoxy)Cinnamic Acid
CAS No.	886501-56-0
Molecular Formula	C₁₀H₆ClF₃O₃
Molecular Weight	266.60 g/mol
Synonyms	(E)-3-[4-Chloro-3-(trifluoromethoxy)phenyl]acrylic acid; 4-Chloro-3-(trifluoromethoxy)cinnamic acid; 3-(4-Chloro-3-(trifluoromethoxy)phenyl)-2-propenoic acid; (2E)-3-[4-Chloro-3-(trifluoromethoxy)phenyl]prop-2-enoic acid; 886501-56-0; Cinnamic acid, 4-chloro-3-(trifluoromethoxy)-; 4-Chloro-α-(trifluoromethoxy)cinnamic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethoxy)Cinnamic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.