Description

3-Fluoro-4-(Trifluoromethoxy)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. This compound is prized for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Electronic Materials: Used in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research: Employed as a versatile reagent in academic and industrial laboratories for exploring new fluorination methodologies and constructing complex molecular architectures.

Basic Information

Product Name	3-Fluoro-4-(Trifluoromethoxy)Benzoic Acid
CAS No.	886498-89-1
Molecular Formula	C8H4F4O3
Molecular Weight	224.11 g/mol
Synonyms	3-Fluoro-4-(trifluoromethoxy)benzoic acid; 4-Trifluoromethoxy-3-fluorobenzoic acid; Benzoic acid, 3-fluoro-4-(trifluoromethoxy)-; 886498-89-1; 3-Fluoro-4-trifluoromethoxybenzoic acid; 3-Fluoro-α,α,α,4-tetramethoxybenzoic acid (incorrect but common misnomer); F-TFMBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.