Description

3,5-Difluoro-2-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by manufacturers of specialty materials and liquid crystal intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro-methoxy pattern can contribute to improved pest selectivity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies, leveraging its molecular structure to influence mesomorphic properties.
• Organic Electronic Materials: Employed in the synthesis of novel organic semiconductors and charge-transport materials for OLEDs and photovoltaic applications.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to construct complex, poly-substituted biaryl systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of client-specific target molecules.

Basic Information

Product Name	3,5-Difluoro-2-Methoxybenzoic Acid
CAS No.	886498-75-5
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-Methoxy-3,5-difluorobenzoic Acid; 3,5-Difluoro-2-methoxybenzoic Acid; Benzoic acid, 3,5-difluoro-2-methoxy-; 886498-75-5; 3,5-Difluoro-o-anisic Acid; 2-Methoxy-3,5-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methoxybenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates, from early-stage R&D to regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.