Description

4,5-Difluoro-2-Methoxybenzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of a substituted benzoyl moiety. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing difluoromethoxybenzene scaffolds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the difluoro-methoxy substitution pattern is required for bioactivity.
• Liquid Crystal & OLED Material Production: Serves as a building block for advanced electronic materials requiring specific fluorine-substituted aromatic cores.
• Polymer Chemistry: Employed as a monomer or modifier in the synthesis of specialty polymers with enhanced thermal or chemical resistance.
• Peptide Coupling Reagent: Acts as an activating agent for carboxylic acids in amide bond formation reactions.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	4,5-Difluoro-2-Methoxybenzoyl Chloride
CAS No.	886498-70-0
Molecular Formula	C9H5ClF2O2
Molecular Weight	218.58 g/mol
Synonyms	2-Methoxy-4,5-difluorobenzoyl chloride; 4,5-Difluoro-2-methoxybenzoic acid chloride; 4,5-Difluoro-o-anisoyl chloride; 2-Methoxy-4,5-difluorobenzoic acid chloride; 886498-70-0; 4,5-Difluoro-2-methoxybenzoyl chloride; Benzoic acid, 4,5-difluoro-2-methoxy-, chloride
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Methoxybenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.