Description

4-(4-Fluoro-Phenyl)-Thiazole-2-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific molecular architecture enables targeted functionality. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, leveraging the bioactivity of the thiazole and fluorophenyl motifs.
• Material Science Research: Serves as a precursor for functionalized organic materials, including ligands for catalysis and components for organic electronic devices.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP or ISO standards for client-specific applications.

Basic Information

Product Name	4-(4-Fluoro-Phenyl)-Thiazole-2-Carboxylic Acid
CAS No.	886366-96-7
Molecular Formula	C10H6FNO2S
Molecular Weight	223.22 g/mol
Synonyms	4-(4-Fluorophenyl)-1,3-thiazole-2-carboxylic acid; 2-Thiazolecarboxylic acid, 4-(4-fluorophenyl)-; 4-(p-Fluorophenyl)thiazole-2-carboxylic acid; 886366-96-7; 4-(4-Fluorophenyl)-2-thiazolecarboxylic acid; 4-(4-Fluorophenyl)thiazole-2-carboxylic acid; 4-(4-Fluorophenyl)-1,3-thiazole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(4-Fluoro-Phenyl)-Thiazole-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.