Description

2-Biphenyl-3',5'-Difluoro-Acetic Acid CAS NO 886363-23-1 is a high-purity, fluorinated biphenyl acetic acid derivative. This compound serves as a critical building block in advanced organic synthesis, particularly valued for its role in creating complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of new active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the biphenyl and fluorine motifs enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, due to its conjugated biphenyl system.
• Fluorine Chemistry Studies: Acts as a model compound in academic and industrial research focused on introducing fluorine atoms into complex organic molecules.
• Fine Chemical Production: An essential intermediate for manufacturing other high-value, fluorinated specialty chemicals.

Basic Information

Product Name	2-Biphenyl-3',5'-Difluoro-Acetic Acid
CAS No.	886363-23-1
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	[2-(3',5'-Difluorobiphenyl-2-yl)]acetic Acid; 2-(3',5'-Difluoro[1,1'-biphenyl]-2-yl)acetic Acid; 3',5'-Difluoro-2-biphenylacetic Acid; 2-Biphenyl-3',5'-difluoroacetic Acid; (3',5'-Difluoro[1,1'-biphenyl]-2-yl)acetic Acid; Biphenyl-3',5'-difluoro-acetic acid; 886363-23-1 (CAS Name)
EINECS	Contact for details

Quality Control

Our 2-Biphenyl-3',5'-Difluoro-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.