Description

2-(3,5-Difluorophenyl)-2-Methylpropanoic Acid is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly for its role in constructing complex molecules with specific biological activity. Pharmaceutical R&D and fine chemical manufacturers need this material for creating novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the difluorophenyl moiety imparts desired activity and stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced materials with unique properties.
• Ligand and Catalyst Development: Employed in the creation of complex ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and new fluorination methodologies in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-(3,5-Difluorophenyl)-2-Methylpropanoic Acid
CAS No.	879904-44-6
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2-(3,5-Difluorophenyl)-2-methylpropanoic acid; α,α-Dimethyl-3,5-difluorobenzenepropanoic acid; 3,5-Difluoro-α,α-dimethylbenzenepropanoic acid; 2-Methyl-2-(3,5-difluorophenyl)propanoic acid; 879904-44-6; 2-(3,5-Difluorophenyl)-2-methylpropionic acid
EINECS	Contact for details

Quality Control

Our 2-(3,5-Difluorophenyl)-2-Methylpropanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.