Description

2-(4-Fluorophenyl)Cyclopropanecarboxylic Acid is a high-value fluorinated cyclopropane derivative, a crucial chiral building block in modern synthetic chemistry. Its unique strained-ring structure combined with the fluorophenyl moiety makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the preparation of advanced pesticides and herbicides, where the fluorinated cyclopropane unit can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where its rigid structure influences material properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	2-(4-Fluorophenyl)Cyclopropanecarboxylic Acid
CAS No.	879324-64-8
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	2-(4-Fluorophenyl)cyclopropanecarboxylic acid; 2-(p-Fluorophenyl)cyclopropanecarboxylic Acid; 4-Fluoro-α-(1-carboxycyclopropyl)benzene; (1R,2S)-rel-2-(4-Fluorophenyl)cyclopropanecarboxylic Acid (for chiral forms); Cyclopropanecarboxylic acid, 2-(4-fluorophenyl)-; FCPCA
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our production of 2-(4-Fluorophenyl)Cyclopropanecarboxylic Acid adheres to strict in-process controls, with final product release contingent on comprehensive analytical testing. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles. We support customer audits and can provide materials to meet various regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, temperatures between 2°C and 8°C are recommended to maintain optimal stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.