Description

3,4-Difluoro-2-Methoxybenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methoxy substituents, which are instrumental for modulating the electronic and steric properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro-methoxy benzoate core contributes to enhanced biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic compounds used in electronic display technologies, contributing to improved performance and durability.
• Polymer Chemistry: Acts as a monomer or modifier for synthesizing specialty polymers with tailored thermal, chemical, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce a functionalized benzoic acid moiety into complex molecular architectures.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process chemistry, and material science research in academic and industrial R&D laboratories.

Basic Information

Product Name	3,4-Difluoro-2-Methoxybenzoic Acid
CAS No.	875664-52-1
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	2-Methoxy-3,4-difluorobenzoic Acid; 3,4-Difluoro-2-methoxybenzoic Acid; Benzoic acid, 3,4-difluoro-2-methoxy-; 875664-52-1; 3,4-Difluoro-o-anisic Acid; 2-Methoxy-3,4-difluorobenzoic acid
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Methoxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.